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Article

Analysis of the MMP-9 (C-1562 T) and TIMP-2 (G-418C) gene promoter polymorphisms in patients with chronic periodontitis.

Journal of clinical periodontology - 1 Feb 2005

de Souza A P, Trevilatto P C, Scarel-Caminaga R M, de Brito R B, Barros S P, Line S R P

Abstract excerpt

BACKGROUND: Matrix metalloproteinases (MMP)-9 is an important member of the matrix metalloproteinase family. A functional polymorphism has been described in the promoter region of the human MMP-9 gene. A C-to-T base exchange at -1562 creates two different alleles, and the C/T and T/T genotypes promote high activity of the MMP-9 gene promoter, increasing the risk for inflammatory diseases. The metalloproteinase-2...

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Identifiers

PMID: 15691353
DOI: 10.1111/j.1600-051X.2005.00665.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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