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Article

Live tuberculosis vaccines based on phoP mutants: a step towards clinical trials.

Expert opinion on biological therapy - 1 Feb 2008

Asensio Jesus A Gonzalo, Arbués Ainhoa, Pérez Esther, Gicquel Brigitte, Martin Carlos

Abstract excerpt

Bacillus Calmette-Guérin (BCG) is the only preventive treatment for tuberculosis in humans, but this live vaccine confers variable protection against pulmonary tuberculosis in adults. Advances in the understanding of Mycobacterium tuberculosis immunopathogenesis have renewed hopes of developing new prophylactic vaccines conferring better protection than BCG. The authors describe here state-of-the-art attenuated...

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Identifiers

PMID: 18194076
DOI: 10.1517/14712598.8.2.201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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