Article
New tuberculosis vaccines based on attenuated strains of the Mycobacterium tuberculosis complex.
Immunology and cell biology - 1 Aug 2000
Collins D M
Abstract excerpt
The world urgently needs a better tuberculosis vaccine. Bacille Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, has been very widely used as a vaccine for many years but has had no major effect on reducing the incidence of tuberculosis. A number of alternative living and non-living vaccines are being investigated. Live vaccine candidates include genetically modified forms of BCG, genetically...
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