Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Meta-analysis of genetic variability in the beta-amyloid production, aggregation and degradation metabolic pathways and the risk of Alzheimer's disease.

Acta neurologica Scandinavica - 1 Jan 2008

Llorca J, Rodríguez-Rodríguez E, Dierssen-Sotos T, Delgado-Rodríguez M, Berciano J, Combarros O

Abstract excerpt

BACKGROUND: Variants in genes encoding enzymes involved in production, aggregation or degradation of beta-amyloid are potential risk factors for sporadic Alzheimer's disease (AD). METHODS: Meta-analyses on AD association with BACE1 exon 5, BACE1 intron 5, FE65 intron 13, CYP46 intron 2, alpha(1)-antichymotrypsine Ala17Thr, bleomycin hydrolase I443V, lectin-like oxidized low-density lipoprotein receptor (OLR1)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Amyloid Precursor Protein Secretases

Share to Asian People

Share to Aspartic Acid Endopeptidases

Share to Receptors, LDL

Share to Scavenger Receptors, Class E

Source

Identifiers

PMID: 17854420
DOI: 10.1111/j.1600-0404.2007.00899.x

Genes

BACE1
OLR1
VLDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Meta-analysis of genetic variability in the beta-amyloid production, aggregation and degradation metabolic pathways and the risk of Alzheimer's disease.PMID 17854420Read ↗

Meta-analysis of BACE1 gene rs638405 polymorphism and the risk of Alzheimer's disease in Caucasion and Asian population.Semantic proximity Read ↗

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer’s DiseaseSemantic proximity Read ↗

[Genetics of late-onset Alzheimer's disease: vascular risk and beta-amyloid metabolism].Semantic proximity Read ↗

Association of BACE1 gene polymorphism with Alzheimer's disease in Asian populations: meta-analysis including Korean samples.Semantic proximity Read ↗

Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease.Semantic proximity Read ↗

Meta-analyses of 8 polymorphisms associated with the risk of the Alzheimer's disease.Semantic proximity Read ↗

A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly.Semantic proximity Read ↗

Association study between Alzheimer's disease and genes involved in Abeta biosynthesis, aggregation and degradation: suggestive results with BACE1.Semantic proximity Read ↗

OAS1 rs1131454 genetic variant is associated with Alzheimer's disease: an epidemiological analysis.Semantic proximity Read ↗

Relationship between the polymorphism in exon 5 of BACE1 gene and Alzheimer's disease.Semantic proximity Read ↗

Alzheimer's Disease and Effects of ABCA7 Polymorphisms: A Review.Semantic proximity Read ↗

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.