Association of BACE1 gene polymorphism with Alzheimer's disease in Asian populations: meta-analysis including Korean samples.

doi:10.1159/000112918

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Article

Association of BACE1 gene polymorphism with Alzheimer's disease in Asian populations: meta-analysis including Korean samples.

Dementia and geriatric cognitive disorders - 1 Jan 2008

Jo Sangmee A, Ahn Kyungsook, Kim Eunkyung, Kim Hwa-Su, Jo Inho, Kim Doh Kwan, Han Changsoo, Park Moon Ho

Abstract excerpt

BACKGROUND: Beta-site amyloid precursor protein cleaving enzyme (BACE) is a candidate risk factor for Alzheimer's disease (AD) from its key role in beta-amyloid generation. Previous genetic association studies of BACE1 gene have yielded conflicting results. This study is an attempt to clarify whether the common SNP in exon 5 of BACE1 (rs638405, Val262) is associated with a risk for late-onset AD. METHODS: We...

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PMID: 18182766
DOI: 10.1159/000112918

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BACE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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