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Article

BACE1 gene promoter single-nucleotide polymorphisms in Alzheimer's disease.

Journal of molecular neuroscience : MN - 1 Sept 2010

Zhou Weihui, Cai Fang, Li Yu, Yang George S, O'Connor Kathleen D, Holt Robert A, Song Weihong

Abstract excerpt

Alzheimer's disease (AD) is the most neurodegenerative disorder leading to dementia. Neuritic plaque formation in brains is a hallmark of AD pathogenesis. Amyloid beta protein (Abeta) is the central component of neuritic plaques. Processing beta-amyloid precursor protein (APP) at the beta-secreta...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 20455082
DOI: 10.1007/s12031-010-9381-6

Genes

BACE1
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20455082-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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