Article
Can estimates of antimalarial efficacy from field studies be improved?
Trends in parasitology - 1 Feb 2008
Gatton Michelle L, Cheng Qin
Abstract excerpt
Monitoring therapeutic efficacy of antimalarial drugs is important because treatment failure rates are the primary basis for changing antimalarial treatment policy. An important aspect of efficacy studies is the use of PCR genotyping to distinguish recrudescent from new infections. The conclusions reached using this technique might be misleading if there is insufficient parasite diversity or a non-uniform...
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