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Article

Some considerations in the design and interpretation of antimalarial drug trials in uncomplicated falciparum malaria

1 Dec 2006

Abstract excerpt

BACKGROUND: Treatments for uncomplicated falciparum malaria should have high cure rates. The World Health Organization has recently set a target cure rate of 95% assessed at 28 days. The use of more effective drugs, with longer periods of patient follow-up, and parasite genotyping to distinguish recrudescence from reinfection raise issues related to the design and interpretation of antimalarial treatment trials...

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PMID: 17187673
DOI: 10.1186/1475-2875-5-127

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