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Article

Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy.

The Journal of infectious diseases - 15 Jan 2008

Bochud Pierre-Yves, Hawn Thomas R, Siddiqui M Ruby, Saunderson Paul, Britton Sven, Abraham Isaac, Argaw Azeb Tadesse, Janer Marta, Zhao Lue Ping, Kaplan Gilla, Aderem Alan

Abstract excerpt

BACKGROUND: Leprosy is characterized by a spectrum of clinical manifestations that depend on the type of immune response against the pathogen. Patients may undergo immunological changes known as "reactional states" (reversal reaction and erythema nodosum leprosum) that result in major clinical deterioration. The goal of the present study was to assess the effect of Toll-like receptor 2 (TLR2) polymorphisms on...

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Identifiers

PMID: 18177245
DOI: 10.1086/524688
PMCID: PMC3077295

Genes

TLR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy.PMID 18177245Read ↗

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