Article
Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states.
The Journal of infectious diseases - 1 May 2010
Berrington William Richard, Macdonald Murdo, Khadge Saraswoti, Sapkota Bishwa Raj, Janer Marta, Hagge Deanna Alisa, Kaplan Gilla, Hawn Thomas Richard
Abstract excerpt
BACKGROUND: Because of its wide spectrum of clinical manifestations and its well-defined immunological complications, leprosy is a useful disease for studying genetic regulation of the host response to infection. We hypothesized that polymorphisms in the nucleotide-binding oligomerization domain...
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