Article
The role of beta-endorphin in the acute motor stimulatory and rewarding actions of cocaine in mice.
Psychopharmacology - 1 Apr 2008
Marquez Paul, Baliram Ramkumarie, Dabaja Ibrahim, Gajawada Nagaraju, Lutfy Kabirullah
Abstract excerpt
RATIONALE: Opioid receptor antagonists have been shown to attenuate the rewarding and addictive effects of cocaine. Furthermore, cocaine has been shown to cause the release of beta-endorphin, an endogenous opioid peptide. OBJECTIVE: We assessed whether this neuropeptide would play a functional ro...
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