Article
Total serum IgA levels and HLA-DQB1*02:01 allelic status.
Immunologic research - 1 Feb 2024
Abdukhakimova Diyora, Ibrayeva Malika, Dossybayeva Kuanysh, Turganbekova Aida, Zhanzakova Zhuldyz, Abdrakhmanova Saniya, McLoone Pauline, Poddighe Dimitri
Abstract excerpt
Immunoglobulin A Deficiency (IgAD) is the most common primary immunodeficiency and is significantly associated with Celiac Disease (CD), which recognizes a specific background of human leukocyte antigens (HLA) predisposition (including HLA-DQB1*02:01 allele). A number of studies investigated the role of HLA in IgAD etiopathogenesis: HLA-DQB1*02 alleles are included in the main haplotypes linked to this primary...
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