Article
Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, SC01, DR3] conserved extended haplotype.
Tissue antigens - 1 Sept 2000
Alper C A, Marcus-Bagley D, Awdeh Z, Kruskall M S, Eisenbarth G S, Brink S J, Katz A J, Stein R, Bing D H, Yunis E J, Schur P H
Abstract excerpt
The extended major histocompatibility complex (MHC) haplotype [HLA-B8, SC01, DR3] is increased in frequency among patients with immunoglobulin (Ig)A deficiency and common variable immunodeficiency. Because the genomic region from HLA-B to HLA-DR/DQ is virtually the same on all instances of the ha...
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