Article
Caucasian origin of disease associated HLA haplotypes in chinese blood donors with IgA deficiency.
Journal of clinical immunology - 1 Feb 2014
Wang Ning, Lu Ping, Ling Bing, Zhu Ziyan, Hammarström Lennart
Abstract excerpt
PURPOSE: Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasians with a prevalence of 1:600. However, the prevalence of IgAD is markedly lower in East Asian countries but no genetic studies have been performed on IgAD individuals in the Mongoloid population. METHODS: We investigated the prevalence of IgAD in a large number of Chinese blood donors (n = 39,015) in...
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