Caucasian origin of disease associated HLA haplotypes in chinese blood donors with IgA deficiency.

doi:10.1007/s10875-013-9983-1

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Article

Caucasian origin of disease associated HLA haplotypes in chinese blood donors with IgA deficiency.

Journal of clinical immunology - 1 Feb 2014

Wang Ning, Lu Ping, Ling Bing, Zhu Ziyan, Hammarström Lennart

Abstract excerpt

PURPOSE: Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasians with a prevalence of 1:600. However, the prevalence of IgAD is markedly lower in East Asian countries but no genetic studies have been performed on IgAD individuals in the Mongoloid population. METHODS: We investigated the prevalence of IgAD in a large number of Chinese blood donors (n = 39,015) in...

Topics

Alleles
Antibodies, Anti-Idiotypic
Asian People
Blood Donors
China
Gene Frequency
Haplotypes
Histocompatibility Antigens
Humans
IgA Deficiency
Immunoglobulin A
Prevalence

Source

Open in PubMed

Identifiers

PMID: 24402621
DOI: 10.1007/s10875-013-9983-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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