Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DRD2 TaqIA polymorphism and demand of dopaminergic medication in Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 15 Mar 2008

Paus Sebastian, Grünewald Anne, Klein Christine, Knapp Michael, Zimprich Alexander, Janetzky Bernd, Möller Jens C, Klockgether Thomas, Wüllner Ullrich

Abstract excerpt

Previous studies have demonstrated that the TaqIA polymorphism of the D2 dopamine receptor gene (DRD2) is associated with response to dopaminergic and antidopaminergic treatment in Parkinson's disease (PD) and schizophrenia, respectively. We tested whether the TaqIA genotype in PD is responsible for demand of dopaminergic medication, measured in total dopaminergic load per year of disease, in a large scale...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Dopamine Agonists

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Levodopa

Share to Parkinson Disease

Share to Polymorphism, Genetic

Share to Receptors, Dopamine D2

Share to Treatment Outcome

Source

Identifiers

PMID: 18175338
DOI: 10.1002/mds.21901

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DRD2 TaqIA polymorphism and demand of dopaminergic medication in Parkinson's disease.PMID 18175338Read ↗

The dopamine D2 receptor gene is a susceptibility locus for Parkinson's disease.Semantic proximity Read ↗

DRD2 haplotype is associated with dyskinesia induced by levodopa therapy in Parkinson's disease patients.Semantic proximity Read ↗

Dopamine D2 receptor TaqIA and TaqIB polymorphisms in Parkinson's disease.Semantic proximity Read ↗

Role of genetic polymorphisms of the dopaminergic system in Parkinson's disease patients with impulse control disorders.Semantic proximity Read ↗

Allelic association between the DRD2 TaqI A polymorphism and Parkinson's disease.Semantic proximity Read ↗

Taq1A polymorphism in the dopamine D2 receptor gene as a predictor of clinical response to aripiprazole.Semantic proximity Read ↗

Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution.Semantic proximity Read ↗

Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers.Semantic proximity Read ↗

Dopamine D2 receptor gene polymorphism and the risk of levodopa-induced dyskinesias in PD.Semantic proximity Read ↗

D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele.Semantic proximity Read ↗

Task-dependent interactions between dopamine D2 receptor polymorphisms and L-DOPA in patients with Parkinson's disease.Semantic proximity Read ↗

The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.