Article
Dopamine D2 receptor TaqIA and TaqIB polymorphisms in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 May 2003
Tan Eng-King, Tan Yanni, Chai Anthea, Tan Christopher, Shen Hui, Lum Sau-Ying, Fook-Cheong Stephanie M C, Teoh Mei-Ling, Yih Yuan, Wong Meng-Cheong, Zhao Yi
Abstract excerpt
In a case control study, we examined the association of DRD2 Taq1A and Taq1B polymorphisms and risk of PD, and evaluated the strength of linkage disequilibrium of the polymorphisms. The Taq1A and Taq1B polymorphisms were in strong linkage disequilibrium. There was, however, no significant association of the two polymorphisms with PD.
Topics
- Alleles
- Analysis of Variance
- DNA Primers
- Female
- Gene Frequency
- Genetic Markers
- Genetic Predisposition to Disease
- Genotype
- Humans
- Linkage Disequilibrium
- Male
