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Article

Maximum likelihood estimates of two-locus recombination fractions under some natural inequality restrictions.

BMC genetics - 4 Jan 2008

Zhou Ying, Shi Ning-Zhong, Fung Wing-Kam, Guo Jianhua

Abstract excerpt

BACKGROUND: The goal of linkage analysis is to determine the chromosomal location of the gene(s) for a trait of interest such as a common disease. Three-locus linkage analysis is an important case of multi-locus problems. Solutions can be found analytically for the case of triple backcross mating. However, in the present study of linkage analysis and gene mapping some natural inequality restrictions on parameters...

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Identifiers

PMID: 18173855
DOI: 10.1186/1471-2156-9-1
PMCID: PMC2249595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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