Article
Recombination fraction in pre-recombinant inbred lines (PRERIL) - revisiting a century old problem in genetics.
BMC genomics - 2 Sept 2024
Xu Shizhong, Osorio Y Fortéa José
Abstract excerpt
BACKGROUND: Traditional recombinant inbred lines (RILs) are generated from repeated self-fertilization or brother-sister mating from the F1 hybrid of two inbred parents. Compared with the F2 population, RILs cumulate more crossovers between loci and thus increase the number of recombinants, resulting in an increased resolution of genetic mapping. Since they are inbred to the isogenic stage, another consequence of...
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