Article
A multilocus likelihood approach to joint modeling of linkage, parental diplotype and gene order in a full-sib family.
BMC genetics - 26 Jul 2004
Lu Qing, Cui Yuehua, Wu Rongling
Abstract excerpt
BACKGROUND: Unlike a pedigree initiated with two inbred lines, a full-sib family derived from two outbred parents frequently has many different segregation types of markers whose linkage phases are not known prior to linkage analysis. RESULTS: We formulate a general model of simultaneously estimating linkage, parental diplotype and gene order through multi-point analysis in a full-sib family. Our model is based...
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