ras oncogene activation and occupational exposures in acute myeloid leukemia.

doi:10.1093/jnci/84.21.1626

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Article

ras oncogene activation and occupational exposures in acute myeloid leukemia.

Journal of the National Cancer Institute - 4 Nov 1992

Taylor J A, Sandler D P, Bloomfield C D, Shore D L, Ball E D, Neubauer A, McIntyre O R, Liu E

Abstract excerpt

BACKGROUND: Epidemiologic studies of acute myeloid leukemias (AMLs) show small increases in risk of disease associated with certain occupations and chemical exposures. PURPOSE: This study was designed to determine whether the presence of mutationally activated ras oncogenes in AML are associated with occupational and chemical exposures. METHODS: We interviewed 62 patients with newly diagnosed AML (or their...

Topics

Acute Disease
Adult
Aged
Case-Control Studies
Codon
Female
Gene Expression Regulation, Leukemic
Genes, ras
Humans
Leukemia, Erythroblastic, Acute
Leukemia, Monocytic, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, Myeloid

Leukemia, Myeloid, Acute

Leukemia, Myelomonocytic, Acute

Male

Middle Aged

Mutation

Occupational Exposure

Source

Open in PubMed

Identifiers

PMID: 1433344
DOI: 10.1093/jnci/84.21.1626

Genes

HRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1433344-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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