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Article

Etiology-dependent molecular mechanisms in human hepatocarcinogenesis

26 Dec 2007

Abstract excerpt

UNLABELLED: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is characterized by aggressive tumor behavior coupled with poor prognosis. Various etiologies have been linked to HCC development, most prominently chronic hepatitis B and C virus infections as well as chronic alcohol consumption. In approximately 10% of HCCs, the etiology remains cryptic; however, recent epidemiological...

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PMID: 18161050
DOI: 10.1002/hep.22033

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