Article
Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease.
Retrovirology - 20 Oct 2006
Zhang Hong, Hoffmann Federico, He Jun, He Xiang, Kankasa Chipepo, West John T, Mitchell Charles D, Ruprecht Ruth M, Orti Guillermo, Wood Charles
Abstract excerpt
BACKGROUND: The causal mechanisms of differential disease progression in HIV-1 infected children remain poorly defined, and much of the accumulated knowledge comes from studies of subtype B infected individuals. The applicability of such findings to other subtypes, such as subtype C, remains to be substantiated. In this study, we longitudinally characterized the evolution of the Env V1-V5 region from seven...
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