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Article

Mutator mutants of Escherichia coli carrying a defect in the DNA polymerase III tau subunit.

Molecular microbiology - 1 Feb 2006

Pham Phuong T, Zhao Wei, Schaaper Roel M

Abstract excerpt

To investigate the possible role of accessory subunits of Escherichia coli DNA polymerase III holoenzyme (HE) in determining chromosomal replication fidelity, we have investigated the role of the dnaX gene. This gene encodes both the tau and gamma subunits of HE, which play a central role in the organization and functioning of HE at the replication fork. We find that a classical, temperature-sensitive dnaX...

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PMID: 16430690
DOI: 10.1111/j.1365-2958.2005.05011.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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