Article
Prediction of salt and mutational effects on the association rate of U1A protein and U1 small nuclear RNA stem/loop II.
The journal of physical chemistry. B - 15 May 2008
Qin Sanbo, Zhou Huan-Xiang
Abstract excerpt
We have developed a computational approach for predicting protein-protein association rates (Alsallaq and Zhou, Structure 2007, 15, 215). Here we expand the range of applicability of this approach to protein-RNA binding and report the first results for protein-RNA binding rates predicted from atomistic modeling. The system studied is the U1A protein and stem/loop II of the U1 small nuclear RNA. Experimentally it...
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