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Article

Evidence of hypothalamic degeneration in the anorectic anx/anx mouse.

Glia - 1 Jan 2011

Nilsson Ida A K, Thams Sebastian, Lindfors Charlotte, Bergstrand Anita, Cullheim Staffan, Hökfelt Tomas, Johansen Jeanette E

Abstract excerpt

Mice homozygous for the anorexia (anx) mutation are characterized by poor food intake and death by three to five weeks after birth. By P21 these mice display lower density of hypothalamic neuropeptides, including Agouti gene-related protein (AGRP). The AGRP/neuropeptide Y (NPY) system of the anx/...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20967882
DOI: 10.1002/glia.21075

Genes

AGRP
NPY
POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20967882-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

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Evidence of hypothalamic degeneration in the anorectic anx/anx mouse.PMID 20967882Read ↗

Aberrant agouti-related protein system in the hypothalamus of the anx/anx mouse is associated with activation of microglia.Semantic proximity Read ↗

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Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse.Semantic proximity Read ↗

Hypothalamus transcriptome profile suggests an anorexia-cachexia syndrome in the anx/anx mouse model.Semantic proximity Read ↗

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Approaches to anorexia in rodents: focus on the anx/anx mouse.Semantic proximity Read ↗

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