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An imprinted transcript, antisense to <i>Nesp,</i> adds complexity to the cluster of imprinted genes at the mouse <i>Gnas</i> locus

14 Mar 2000

Abstract excerpt

The Gnas locus in distal mouse chromosome (Chr) 2 is emerging as a complex genomic region. It contains three imprinted genes in the order Nesp-Gnasxl-Gnas. Gnas encodes a G protein alpha-subunit, and Nesp and Gnasxl encode proteins of unknown function expressed in neuroendocrine tissue. Together, these genes form a single transcription unit because transcripts of Nesp and Gnasxl are alternatively spliced onto...

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PMID: 10716699
DOI: 10.1073/pnas.97.7.3342

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