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Article

Imprinting on chromosome 20: tissue-specific imprinting and imprinting mutations in the GNAS locus.

American journal of medical genetics. Part C, Seminars in medical genetics - 15 Aug 2010

Kelsey Gavin

Abstract excerpt

The GNAS locus on chromosome 20q13.11 is the archetypal complex imprinted locus. It comprises a bewildering array of alternative transcripts determined by differentially imprinted promoters which encode distinct proteins. It also provides the classic example of tissue-specific imprinted gene expression, in which the canonical GNAS transcript coding for Gsalpha is expressed predominantly from the maternal allele...

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Share to Base Sequence
Share to Chromogranins
Share to Chromosomes, Human, Pair 20

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Genomic Imprinting

Share to GTP-Binding Protein alpha Subunits, Gs

Share to Organ Specificity

Share to Pseudohypoparathyroidism

Source

Identifiers

PMID: 20803660
DOI: 10.1002/ajmg.c.30271

Genes

GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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