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Article

Depression and prostate cancer risk: A Mendelian randomization study.

Cancer medicine - 1 Dec 2020

Chen Xiong, Kong Jianqiu, Diao Xiayao, Cai Jiahao, Zheng Junjiong, Xie Weibin, Qin Haide, Huang Jian, Lin Tianxin

Abstract excerpt

BACKGROUND: The association between depression and prostate carcinogenesis has been reported in observational studies but the causality from depression on prostate cancer (PCa) remained unknown. We aimed to assess the causal effect of depression on PCa using the two-sample Mendelian randomization (MR) method. METHODS: Two sets of genetics instruments were used for analysis, derived from publicly available genetic...

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Identifiers

PMID: 33027558
DOI: 10.1002/cam4.3493
PMCID: PMC7724297

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