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Article

Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study.

PloS one - 1 Jan 2013

Kondo Kenji, Ikeda Masashi, Kajio Yusuke, Saito Takeo, Iwayama Yoshimi, Aleksic Branko, Yamada Kazuo, Toyota Tomoko, Hattori Eiji, Ujike Hiroshi, Inada Toshiya, Kunugi Hiroshi, Kato Tadafumi, Yoshikawa Takeo, Ozaki Norio, Iwata Nakao

Abstract excerpt

BACKGROUND: Recent genome-wide association studies (GWASs) investigating bipolar disorder (BD) have detected a number of susceptibility genes. These studies have also provided novel insight into shared genetic components between BD and schizophrenia (SCZ), two major psychotic disorders. To examine the replication of the risk variants for BD and the pleiotropic effect of the variants associated with BD, we...

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Identifiers

PMID: 23967141
DOI: 10.1371/journal.pone.0070964
PMCID: PMC3742587

Genes

PBRM1

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