Article
Constant allelic alteration on chromosome 16p (TSC2 gene) in perivascular epithelioid cell tumour (PEComa): genetic evidence for the relationship of PEComa with angiomyolipoma.
The Journal of pathology - 1 Feb 2008
Pan C-C, Chung M-Y, Ng K-F, Liu C-Y, Wang J-S, Chai C-Y, Huang S-H, Chen P C-H, Ho D M T
Abstract excerpt
Perivascular epithelioid cell tumours (PEComas) are a family of tumours including classic angiomyolipoma, lymphangioleiomyomatosis, and clear epithelioid cell tumours reported under a variety of names such as epithelioid angiomyolipoma, pulmonary and extrapulmonary clear cell sugar tumour, and PEComa. Our previous comparative genomic hybridization study of PEComas demonstrated recurrent chromosomal aberrations...
Topics
- Adolescent
- Adult
- Alleles
- Angiomyolipoma
- Biomarkers, Tumor
- Case-Control Studies
- Child
- Chromosome Mapping
- Female
- Humans
- Immunohistochemistry
- Kidney Neoplasms
- Liver Neoplasms
- Loss of Heterozygosity