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Article

Molecular Pathology of Lymphangioleiomyomatosis and Other Perivascular Epithelioid Cell Tumors

1 Jan 2010

Abstract excerpt

Abstract Context. Lymphangioleiomyomatosis (LAM) is a cystic lung disease that can be included in the wide group of proliferative lesions named PEComas (perivascular epithelioid cell tumors). These proliferative tumors are characterized by the coexpression of myogenic and melanogenesis-related markers. In all these lesions, genetic alterations related to the tuberous sclerosis complex (TSC) have been...

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PMID: 20073603
DOI: 10.5858/2008-0542-rar1.1

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