Article
Downregulation of TESTIN and its association with cancer history and a tendency toward poor survival in head and neck squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery - 1 Mar 2009
Gunduz Esra, Gunduz Mehmet, Beder Levent, Nagatsuka Hitoshi, Fukushima Kunihiro, Sutcu Recep, Delibas Namik, Yamanaka Noboru, Shimizu Kenji, Nagai Noriyuki
Abstract excerpt
OBJECTIVE: To examine the role of TESTIN as a candidate tumor suppressor gene in head and neck carcinogenesis. DESIGN: Mutation and messenger RNA (mRNA) expression analyses. SETTING: Academic research. PATIENTS: Paired normal and tumor samples were obtained from 38 patients with primary head and neck squamous cell carcinoma. MAIN OUTCOME MEASURES: Analysis and comparison of TESTIN gene mRNA expression and its...
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