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Serum levels of angiogenic factors indicate a pro‐angiogenic state in adults with sickle cell disease

24 Apr 2006

Abstract excerpt

Hypoxia-induced angiogenesis may play an important role in the pathophysiology of sickle cell disease (SCD). Serum levels of angiopoietin (Ang)-1, Ang-2, vascular endothelial growth factor, placenta growth factor (PlGF), soluble tunica intima endothelial kinase 2 (sTIE2), erythropoietin (EPO) and endothelial activation markers (soluble vascular adhesion molecule-1, soluble intercellular adhesion molecule-1) were...

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PMID: 16803577
DOI: 10.1111/j.1365-2141.2006.06103.x

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