Article
Development of multiplex assay for rapid characterization of Mycobacterium tuberculosis.
Journal of clinical microbiology - 1 Feb 2008
Bergval I L, Vijzelaar R N C P, Dalla Costa E R, Schuitema A R J, Oskam L, Kritski A L, Klatser P R, Anthony R M
Abstract excerpt
We have developed a multiplex assay, based on multiplex ligation-dependent probe amplification (MLPA), that allows simultaneous detection of multiple drug resistance mutations and genotype-specific mutations at any location in the Mycobacterium tuberculosis genome. The assay was validated on a re...
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