Article
Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus.
Memorias do Instituto Oswaldo Cruz - 1 Jun 2017
Santos Paula Fernanda Gonçalves Dos, Costa Elis Regina Dalla, Ramalho Daniela M, Rossetti Maria Lucia, Barcellos Regina Bones, Nunes Luciana de Souza, Esteves Leonardo Souza, Rodenbusch Rodrigo, Anthony Richard M, Bergval Indra, Sengstake Sarah, Viveiros Miguel, Kritski Afrânio, Oliveira Martha M
Abstract excerpt
BACKGROUND: To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB), new molecular methods that can routinely be used to screen for a wide range of drug resistance related genetic markers in the Mycobacterium tuberculosis genome are urgently needed. OBJECTIVE: To evaluate the performance of multiplex ligaton-dependent probe amplification (MLPA) against Genotype® MTBDRplus to detect resistance to...
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