Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Optimizing multiplex SNP-based data analysis for genotyping of Mycobacterium tuberculosis isolates.

BMC genomics - 7 Jul 2014

Sengstake Sarah, Bablishvili Nino, Schuitema Anja, Bzekalava Nino, Abadia Edgar, de Beer Jessica, Tadumadze Nona, Akhalaia Maka, Tuin Kiki, Tukvadze Nestani, Aspindzelashvili Rusudan, Bachiyska Elizabeta, Panaiotov Stefan, Sola Christophe, van Soolingen Dick, Klatser Paul, Anthony Richard, Bergval Indra

Abstract excerpt

BACKGROUND: Multiplex ligation-dependent probe amplification (MLPA) is a powerful tool to identify genomic polymorphisms. We have previously developed a single nucleotide polymorphism (SNP) and large sequence polymorphisms (LSP)-based MLPA assay using a read out on a liquid bead array to screen f...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Bacterial
Share to Drug Resistance, Microbial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genotype

Share to Mycobacterium tuberculosis

Share to Nucleic Acid Amplification Techniques

Share to Polymorphism, Single Nucleotide

Share to Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 25001491
DOI: 10.1186/1471-2164-15-572
PMCID: PMC4117977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25001491-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Optimizing multiplex SNP-based data analysis for genotyping of Mycobacterium tuberculosis isolates.PMID 25001491Read ↗

Combined species identification, genotyping, and drug resistance detection of Mycobacterium tuberculosis cultures by MLPA on a bead-based array.Semantic proximity Read ↗

Development of multiplex assay for rapid characterization of Mycobacterium tuberculosis.Semantic proximity Read ↗

Evaluation of SNP-based genotyping to monitor tuberculosis control in a high MDR-TB settingSemantic proximity Read ↗

Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus.Semantic proximity Read ↗

Identification of biomarkers for tuberculosis disease using a novel dual-color RT–MLPA assaySemantic proximity Read ↗

Evaluation of a two-step approach for large-scale, prospective genotyping of Mycobacterium tuberculosis isolates in the United States.Semantic proximity Read ↗

Low cost, low tech SNP genotyping tools for resource-limited areas: Plague in Madagascar as a model.Semantic proximity Read ↗

On-chip ligation of multiplexing probe-pairs for identifying point mutations out of dense SNP loci.Semantic proximity Read ↗

A multiplex bead-based suspension array assay for interrogation of phylogenetically informative single nucleotide polymorphisms for Bacillus anthracis.Semantic proximity Read ↗

Comparative evaluation of ligation-mediated PCR and spoligotyping as screening methods for genotyping of Mycobacterium tuberculosis strains.Semantic proximity Read ↗

Multiplatform comparison of multiplexed bead arrays using HPV genotyping as a test case.Semantic proximity Read ↗

Automatic Identification of Individual rpoB Gene Mutations Responsible for Rifampin Resistance in Mycobacterium tuberculosis by Use of Melting Temperature Signatures Generated by the Xpert MTB/RIF Ultra AssaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.