Article
Loss of polyadenylation protein tauCstF-64 causes spermatogenic defects and male infertility.
Proceedings of the National Academy of Sciences of the United States of America - 18 Dec 2007
Dass Brinda, Tardif Steve, Park Ji Yeon, Tian Bin, Weitlauf Harry M, Hess Rex A, Carnes Kay, Griswold Michael D, Small Christopher L, Macdonald Clinton C
Abstract excerpt
Polyadenylation, the process of eukaryotic mRNA 3' end formation, is essential for gene expression and cell viability. Polyadenylation of male germ cell mRNAs is unusual, exhibiting increased alternative polyadenylation, decreased AAUAAA polyadenylation signal use, and reduced downstream sequence...
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