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Article

Regulation of spermatogenesis by testis-specific, cytoplasmic poly(A) polymerase TPAP.

Science (New York, N.Y.) - 6 Dec 2002

Kashiwabara Shin-Ichi, Noguchi Junko, Zhuang Tiangang, Ohmura Ko, Honda Arata, Sugiura Shin, Miyamoto Kiyoko, Takahashi Satoru, Inoue Kimiko, Ogura Atsuo, Baba Tadashi

Abstract excerpt

Spermatogenesis is a highly specialized process of cellular differentiation to produce spermatozoa. This differentiation process accompanies morphological changes that are controlled by a number of genes expressed in a stage-specific manner during spermatogenesis. Here we show that in mice, the absence of a testis-specific, cytoplasmic polyadenylate [poly(A)] polymerase, TPAP, results in the arrest of...

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Identifiers

PMID: 12471261
DOI: 10.1126/science.1074632

Genes

TAF10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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