Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST).

Cancer - 1 Feb 2008

Dematteo Ronald P, Gold Jason S, Saran Lisa, Gönen Mithat, Liau Kui Hin, Maki Robert G, Singer Samuel, Besmer Peter, Brennan Murray F, Antonescu Cristina R

Abstract excerpt

BACKGROUND: Gastrointestinal stromal tumor (GIST) is the most frequent sarcoma of the intestinal tract and often shows constitutive activation of either the KIT or PDGFRA receptor tyrosine kinases because of gain-of-function mutation. Although the efficacy of tyrosine kinase inhibitors in metasta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation
Share to Gastrointestinal Stromal Tumors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multivariate Analysis

Share to Neoplasm Recurrence, Local

Share to Predictive Value of Tests

Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

Share to Survival Analysis

Source

Identifiers

PMID: 18076015
DOI: 10.1002/cncr.23199

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18076015-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST).PMID 18076015Read ↗

Molecular Features of Gastrointestinal Stromal Tumors: A Single Referral Cancer Center Experience.Semantic proximity Read ↗

KIT and PDGFRA mutations and the risk of GI stromal tumor recurrence.Semantic proximity Read ↗

Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors.Semantic proximity Read ↗

Impact of KIT and PDGFRA gene mutations on prognosis of patients with gastrointestinal stromal tumors after complete primary tumor resection.Semantic proximity Read ↗

Prognostic value of mutational characteristics in gastrointestinal stromal tumors: a single-center experience in 275 cases.Semantic proximity Read ↗

Gastrointestinal stromal tumors: clinical significance of p53 expression, MDM2 amplification, and KIT mutation status.Semantic proximity Read ↗

Prognostic Stratification of High-risk Gastrointestinal Stromal Tumors in the Era of Targeted TherapySemantic proximity Read ↗

Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial.Semantic proximity Read ↗

Clinicopathological and molecular aspects of foregut gastrointestinal stromal tumours.Semantic proximity Read ↗

Prognostic significance of p53 gene mutations and protein overexpression in localized gastrointestinal stromal tumours.Semantic proximity Read ↗

Results on prognostic value of mutations in localized gastrointestinal stromal tumors (GIST) in one single center.Semantic proximity Read ↗

Prognostic value of KIT/PDGFRA mutations in gastrointestinal stromal tumours (GIST): Polish Clinical GIST Registry experience.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.