Article
Prognostic value of mutational characteristics in gastrointestinal stromal tumors: a single-center experience in 275 cases.
Medical oncology (Northwood, London, England) - 1 Jan 2014
Wang Ming, Xu Jia, Zhao Wenyi, Tu Lin, Qiu Weiqing, Wang Chaojie, Shen Yangyin, Liu Qiang, Cao Hui
Abstract excerpt
The objective of this study was to investigate the impact of KIT/PDGFRA mutations on the prognosis of gastrointestinal stromal tumors (GISTs). In the present study, genotype analyses were performed based on GIST samples from 275 patients. The relationship between mutation and clinicopathological characteristics were explored. All factors were evaluated for their impacts on relapse-free survival (RFS). Briefly,...
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