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Article

Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice.

BMC genomics - 11 May 2016

De Simone Maura, Spagnuolo Lorenza, Lorè Nicola Ivan, Cigana Cristina, De Fino Ida, Broman Karl W, Iraqi Fuad A, Bragonzi Alessandra

Abstract excerpt

BACKGROUND: P. aeruginosa is one of the top three causes of opportunistic human bacterial infections. The remarkable variability in the clinical outcomes of this infection is thought to be associated with genetic predisposition. However, the genes underlying host susceptibility to P. aeruginosa infection are still largely unknown. RESULTS: As a step towards mapping these genes, we applied a genome wide linkage...

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Identifiers

PMID: 27169516
DOI: 10.1186/s12864-016-2676-4
PMCID: PMC4866434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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