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Article

A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jul 2003

Denny Paul, Hopes Elaine, Gingles Neill, Broman Karl W, McPheat William, Morten John, Alexander Janet, Andrew Peter W, Brown Steve D M

Abstract excerpt

We have studied the genetics of susceptibility to infection by Streptococcus pneumoniae in mice. Linkage analysis of the F(2) generation from a cross between resistant BALB/cO1aHsd and susceptible CBA/CaO1aHsd strains allowed us to map a major locus controlling the development of bacteremia and survival after intranasal infection.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12925893
DOI: 10.1007/s00335-002-2261-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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