Article
Five common gene variants identify elevated genetic risk for coronary heart disease.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Oct 2007
Bare Lance A, Morrison Alanna C, Rowland Charles M, Shiffman Dov, Luke May M, Iakoubova Olga A, Kane John P, Malloy Mary J, Ellis Stephen G, Pankow James S, Willerson James T, Devlin James J, Boerwinkle Eric
Abstract excerpt
PURPOSE: Because multiple genetic variants influence risk for coronary heart disease, we combined multiple variants that had been associated with coronary heart disease in several studies into a genetic risk score and asked whether a high genetic risk score would be significantly associated with coronary heart disease after accounting for traditional risk factors. METHODS: We considered five variants that were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
