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Article

A functional polymorphism of TIR-domain-containing adaptor protein is not associated with axial spondyloarthritis.

Annals of the rheumatic diseases - 1 May 2008

Cantaert T, Stone M A, ter Borg M, Mogg R, De Vries N, Wilson A G, Tak P P, Baeten D

Abstract excerpt

OBJECTIVE: A genetic variant of the toll-like receptor (TLR)2/4 adaptor protein TIRAP (single nucleotide polymorphism (SNP) C539T) was identified in a UK and in several African populations. The heterozygous genotype of this SNP has been associated with protection from severe infections. This alle...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18073264
DOI: 10.1136/ard.2007.082784

Genes

TIRAP
TLR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18073264-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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