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Article

Clinical characteristics and frequency of TLR4 polymorphisms in Brazilian patients with ankylosing spondylitis.

Revista brasileira de reumatologia - 1 Jan 2000

Machado Natalia Pereira, Nogueira Eliana, Oseki Karen, Ebbing Pâmela Carolina Cruz, Origassa Clarice Silvia Taemi, Mohovic Tatiane, Câmara Niels Olsen Saraiva, Pinheiro Marcelo de Medeiros

Abstract excerpt

OBJECTIVES: Innate immunity is involved in the physiopathology of ankylosing spondylitis (AS), with the participation of Gram-negative bacteria, modulation of human leukocyte antigen (HLA) B27 and the involvement of pattern recognition receptors, such as Toll-like receptors (TLRs). The aim of this study was to investigate the clinical characteristics and frequency of TLR4 polymorphisms (Asp299Gly and Thr 399Ile)...

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Source

Identifiers

PMID: 27692393
DOI: 10.1016/j.rbre.2016.07.004

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Clinical characteristics and frequency of TLR4 polymorphisms in Brazilian patients with ankylosing spondylitis.PMID 27692393Read ↗

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