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Article

Filaggrin mutations confer susceptibility to atopic dermatitis but not to asthma.

The Journal of allergy and clinical immunology - 1 Dec 2007

Rogers Angela J, Celedón Juan C, Lasky-Su Jessica A, Weiss Scott T, Raby Benjamin A

Abstract excerpt

BACKGROUND: Loss-of-function mutations in the filaggrin gene (FLG) have been strongly associated with atopic dermatitis and allergic phenotypes in multiple populations. The role of these mutations in the development of asthma is less clear, particularly in patients who do not have coincident atopic dermatitis. OBJECTIVE: To determine whether FLG mutations are associated with asthma or asthma-related intermediate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18073125
DOI: 10.1016/j.jaci.2007.09.037

Genes

FLG
FEV

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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