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Article

Impact of pathognomonic genetic alterations on the prognosis of papillary thyroid carcinoma. ESES vienna presentation.

Langenbeck's archives of surgery - 1 Sept 2010

Musholt Thomas J, Schönefeld Sonja, Schwarz Christina H, Watzka Felix M, Musholt Petra B, Fottner Christian, Weber Matthias M, Springer Erik, Schad Arno

Abstract excerpt

INTRODUCTION: BRAF mutations and RET or NTRK1 rearrangements were identified as causing events that drive the malignant transformation of the thyroid follicular cell. The impact of these alterations on the course of papillary thyroid carcinoma (PTC) is still unsettled. PATIENTS AND METHODS: Tumor tissues of 290 (98 male, 192 female) patients were intra-operatively snap frozen or harvested from archival...

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Source

Identifiers

PMID: 20640859
DOI: 10.1007/s00423-010-0682-6

Genes

BRAF
NTRK1
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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