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Article

A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalian cells.

FEBS letters - 23 Jan 2008

Zhang Cuizhu, Tang Jun, Xie Jia, Zhang Hongkai, Li Yapeng, Zhang Jie, Verpooten Dustin, He Bin, Cao Youjia

Abstract excerpt

ICP34.5, encoded by herpes simplex virus 1, is a protein phosphatase 1 (PP1) regulatory subunit that mediates dephosphorylation of the alpha subunit of translation initiation factor 2 (eIF2alpha). However, the mechanism of its action remains poorly understood. Here, we show that amino acid substi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18068675
DOI: 10.1016/j.febslet.2007.11.082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18068675-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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