Article
Analysis of streptococcal CRISPRs from human saliva reveals substantial sequence diversity within and between subjects over time.
Genome research - 1 Jan 2011
Pride David T, Sun Christine L, Salzman Julia, Rao Nitya, Loomer Peter, Armitage Gary C, Banfield Jillian F, Relman David A
Abstract excerpt
Viruses may play an important role in the evolution of human microbial communities. Clustered regularly interspaced short palindromic repeats (CRISPRs) provide bacteria and archaea with adaptive immunity to previously encountered viruses. Little is known about CRISPR composition in members of human microbial communities, the relative rate of CRISPR locus change, or how CRISPR loci differ between the microbiota of...
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