Article
The highly dynamic CRISPR1 system of Streptococcus agalactiae controls the diversity of its mobilome.
Molecular microbiology - 1 Sept 2012
Lopez-Sanchez Maria-José, Sauvage Elisabeth, Da Cunha Violette, Clermont Dominique, Ratsima Hariniaina Elisoa, Gonzalez-Zorn Bruno, Poyart Claire, Rosinski-Chupin Isabelle, Glaser Philippe
Abstract excerpt
Clustered regularly interspaced short palindromic repeats (CRISPR) confer immunity against mobile genetic elements (MGEs) in prokaryotes. Streptococcus agalactiae, a leading cause of neonatal infections contains in its genome two CRISPR/Cas systems. We show that type 1-C CRISPR2 is present in few strains but type 2-A CRISPR1 is ubiquitous. Comparative sequence analysis of the CRISPR1 spacer content of 351...
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